Patellar Fracture — Biomarkers & Genes Summary
Biomarker / Gene
Bad Score
Free Actions
Paid Actions
BIOMARKERS
25-OH Vitamin D
<30 ng/mL
Sun 15-30 min/day, fatty fish,
eggs, UV-exposed mushrooms
D3 4000-6000 IU daily
+ K2 MK-7 100-200 mcg
P1NP
Low/flat at wk 6 & 12
Protein 1.2-1.6 g/kg/day, quality
sleep, weight-bearing exercise
Collagen peptides 10-15 g + Vit C
500-1000 mg + ch-OSA 10 mg
β-CTX
Markedly elevated
(+ low P1NP = red flag)
Sleep 7-9 h, calcium-rich diet,
quit smoking, reduce stress
K2 MK-7 180-200 mcg/day
+ omega-3 EPA+DHA 2-4 g
hs-CRP
>3.0 mg/L
Mediterranean diet, 7+ h sleep,
moderate exercise
Omega-3 2-4 g + curcumin
500-1000 mg + quercetin 500 mg
PTH
>65 pg/mL
Calcium-rich foods, sun exposure,
limit caffeine >4 cups/day
Vit D3 (primary correction)
+ calcium citrate 500 mg x2/day
RBC Magnesium
<4.5 mg/dL
Pumpkin seeds, leafy greens,
legumes, reduce alcohol
Mg glycinate/malate 300-400 mg
elemental; take in evening
GENES
VDR
Unfavorable variant
(BsmI, FokI, TaqI)
Midday sun 30-45 min; resistance
exercise (upregulates VDR)
D3 5000-8000 IU + K2 MK-7
200 mcg; retest quarterly
COL1A1
"ss" genotype
(Sp1 rs1800012)
Resistance training, protein
1.4-1.6 g/kg/day, no smoking
Collagen peptides 15 g + Vit C
500-1000 mg + ch-OSA 10 mg
RANKL pathway
(TNFSF11 / TNFRSF11B)
Unfavorable variant
Weight-bearing exercise, stress
management, anti-inflam diet
K2 MK-7 180-200 mcg/day
+ omega-3 EPA+DHA 2-4 g
IL-6 (rs1800795)
GG genotype
Mediterranean diet, quality sleep,
healthy weight, moderate exercise
Omega-3 3-4 g + curcumin
500-1000 mg + quercetin 500 mg
MTHFR (C677T)
TT genotype
Leafy greens, legumes, B12 foods,
avoid alcohol
L-methylfolate 400-1000 mcg
+ methylcobalamin + riboflavin B2