Pseudogout — Genes & Biomarkers Summary
Biomarker / Gene
Bad Score
Free Plan
Plan With Purchases
Serum Calcium
>10.2 mg/dL
Hydrate; stop Ca supplements;
sunlight; avoid high-dose vit A
K2 MK-7 (100–200 mcg/d);
Mg glycinate (200–400 mg/d)
Serum Magnesium
<2.0 mg/dL
or <5.6 RBC Mg
Leafy greens; limit alcohol;
manage stress; review PPIs
Mg glycinate/malate (300–600 mg/d)
PTH (Parathyroid)
>65 pg/mL
Midday sunlight 20–30 min/d;
address kidney function
D3 (2,000–5,000 IU/d)
+ K2 MK-7 (100–200 mcg/d)
Ferritin / TSAT
Ferritin >150 ng/mL
or TSAT >45%
Donate blood; reduce red meat;
tea/coffee with iron-rich meals
IP6 (2–4 g/d on empty stomach);
lactoferrin (200–300 mg/d)
TSH (Thyroid)
>2.5 mIU/L
Brazil nuts (selenium); sleep;
reduce stress; cook cruciferous
Selenium (100–200 mcg/d);
zinc (15–30 mg/d)
hsCRP
>1.0 mg/L
Sleep; anti-inflammatory diet;
zone 2 exercise; reduce stress
Omega-3 EPA+DHA (2–4 g/d);
curcumin+piperine (500–1,000 mg 2×/d)
Serum Phosphate
<2.5 or >4.0 mg/dL
Avoid phosphate additives in
processed foods; whole foods diet
Ca carbonate (phosphate binder,
medical supervision required)
GENETIC SUSCEPTIBILITY FACTORS
ANKH
Gain-of-function
variant
Limit fructose & alcohol;
hydrate; low-impact movement
Mg glycinate (300–500 mg/d);
boron (3–6 mg/d, 3 mo on/1 off)
ENPP1
Risk variant
Reduce visceral fat; optimize
blood glucose; move every 30 min
Quercetin (500–1,000 mg/d);
resveratrol (200–500 mg/d)
TNFRSF11B
(OPG)
Risk variant
Weight-bearing exercise 3–4×/wk;
avoid long-term corticosteroids
K2 MK-7 (100–200 mcg/d);
D3 (2,000–4,000 IU/d)