SLE Biomarkers & Genes — Risk SummaryBiomarker / GeneBad Score / FlagFree ActionsPaid ActionsBIOMARKERSGENESAnti-dsDNA AntibodiesHigh titerUV protection; sleep 7-9h; daily walkVit D3+K2; Omega-3 2-4g; NAC 600mgComplement C3 & C4Low C3 and/or C4Mediterranean diet; prevent infectionsCurcumin BCM-95; infrared saunaCBC: Lymphocytes & PlateletsLymphopenia/cytopeniaSleep 7-9h; no alcohol; TRE 12-16hZinc 15-25mg; Melatonin 0.5-3mgUrine PCR (uPCR)>0.5 g/gBP <130/80; Na <2g/day; avoid NSAIDsACE inhibitor/ARB; home BP monitorESR vs. CRP DiscordanceESR↑ with normal CRPAnti-inflammatory diet; aerobic 30minFish oil 2-4g EPA+DHA; BoswelliaVitamin D (25-OH)<50 ng/mLFatty fish; address malabsorption factorsVit D3 (4-10k IU)+K2; MagnesiumIFN Signature & FerritinIFN+; Ferritin >500 ng/mLSleep schedule; remove IFN triggersNAC 600mg; LDN; AnifrolumabHLA-DRB1DRB1*03:01 / *15:01Reduce AGEs; protect gut mucosaQuercetin 500mg; HydroxychloroquineIRF5CGGGG risk alleleUV protection; sleep; prevent virusesVit D3 5kIU+K2; Resveratrol 500mgSTAT4rs7574865 risk alleleHigh fiber (30+ plants/wk); mindfulnessProbiotics 20B+ CFU; JAK inhibitorsPTPN22R620W variantAddress infections; maintain lean bodyBerberine 500mg x2; autoimmune panelBLKRisk alleleMonitor anti-Ro/La Ab; limit antigensBelimumab (BAFF); Curcumin BCM-95TREX1Pathogenic variantAvoid UV/tobacco; support autophagyFisetin 500mg; STING inhibitor trials