There is a specific kind of depletion that does not show up on a standard blood panel. You sleep, you eat, you are technically functional — but the drive to pursue things that matter has gone quiet. The reward that used to come with effort and accomplishment has become muted.

Living with Prader-Willi syndrome — whether as a parent, caregiver, or the person directly affected — often means navigating a system where explanations feel incomplete and advice feels generic. You hear about growth hormone therapy and caloric restriction.