Popliteal (back of knee) pain

Possible conditions

Semimembranosus Bursitis — 5 Genes And 7 Biomarkers To Track

Pain at the back of the knee that lingers, swells, and returns no matter what you try is a particular kind of frustrating. Semimembranosus bursitis — inflammation of the small fluid-filled sac nestled between the semimembranosus tendon and the medial gastrocnemius — is often underdiagnosed or lumped together with Baker's cyst and generic posterior knee pain.

Popliteal Tendinitis — 5 Genes And 7 Biomarkers To Track

Popliteal tendinitis does not get the same attention as Achilles tendinopathy or patellar tendinitis, but for anyone who has dealt with persistent lateral knee pain while running downhill, cycling, or changing direction repeatedly, it is every bit as frustrating.

Fabella Syndrome — 7 Biomarkers and 5 Genes To Track

Persistent pain at the back of the knee that does not match any clean diagnosis is genuinely disorienting. Fabella syndrome is one of those conditions that falls through the cracks of standard orthopaedic workups — the fabella, a small sesamoid bone embedded in the lateral head of the gastrocnemius muscle, is present in roughly 10 to 40 percent of people and its prevalence has actually been…

Posterior Knee Capsule Tear — 5 Genes And 7 Biomarkers To Track

A posterior knee capsule tear places you in a particular kind of limbo. The injury is painful enough to stop daily activity, but the standard care pathway — rest, some ice, a physiotherapy referral, maybe an MRI — rarely explains why it happened or why recovery is slower for some people than others.

Popliteal Vein Thrombosis: 5 Genes And 6 Biomarkers To Track

A blood clot forming in the popliteal vein — the vessel running behind your knee — is not a random event. For most people who experience popliteal vein thrombosis, there is an underlying biological story that made it possible: a combination of inherited tendencies, acquired shifts in how the blood behaves, and environmental exposures that tipped the balance toward clotting.

Popliteal Adventitial Cyst Disease: 7 Biomarkers and 3 Genes to Track

If you're reading this, you've probably already heard the phrase "rare vascular condition of unknown cause" more than once, and it hasn't told you much. Popliteal adventitial cyst disease, also called cystic adventitial disease (CAD) of the popliteal artery, is one of those diagnoses that shows up on an MRI report with confidence but gets explained to the patient with a shrug.

Popliteus Tendinopathy: 4 Genes and 7 Biomarkers to Track

If you have been dealing with a nagging ache behind the outer or back part of your knee, especially after downhill running, deep squats, or sudden pivoting, you have probably already heard the standard advice: rest it, ice it, stretch the hamstrings, maybe try some eccentric loading.

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